22 Development of DOUBLE NICKASE CRISPR aganist latently infected human immunodeficency virus (HIV)
نویسندگان
چکیده
منابع مشابه
Rapid CRISPR/Cas9-Mediated Cloning of Full-Length Epstein-Barr Virus Genomes from Latently Infected Cells.
Herpesviruses have relatively large DNA genomes of more than 150 kb that are difficult to clone and sequence. Bacterial artificial chromosome (BAC) cloning of herpesvirus genomes is a powerful technique that greatly facilitates whole viral genome sequencing as well as functional characterization of reconstituted viruses. We describe recently invented technologies for rapid BAC cloning of herpes...
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PURPOSE This study assessed the association of caries, plaque accumulation, gingival health, and antiretroviral therapy (AT) with oral lesion prevalence in human immunodeficiency virus (HIV)-infected Romanian children. METHODS A convenience sample of HIV-infected children who received dental care in 2 hospitals were evaluated for oral lesions, caries (dfs+DFS/total teeth present), plaque (PI,...
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Primary infection with human cytomegalovirus (HCMV) results in the establishment of a lifelong infection of the host which is aided by the ability of HCMV to undergo a latent infection. One site of HCMV latency in vivo is in haematopoietic progenitor cells, resident in the bone marrow, with genome carriage and reactivation being restricted to the cells of the myeloid lineage. Until recently, HC...
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HIV infection is a chronic disease in which different endocrine glands could be involved either directly by the virus itself or indirectly by many factors especially oportunistic infections at the late stages of the disease. bacause the duration and the manifestations of the infection is related to the General factors, we evaluated the hypophysial, thyroid, adrenal and the gonadal hormones in 1...
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Background: Oral lesions are among the earliest clinical manifestations of human immunodeficiency (HIV) infection and are important in early diagnosis and for monitoring the progression to acquired immunodeficiency syndrome (AIDS). The purpose of this study was to determine the prevalence of oral lesions and their relationship with a number of factors in HIV/AIDS patients attending an HIV cente...
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ژورنال
عنوان ژورنال: Journal of Virus Eradication
سال: 2016
ISSN: 2055-6640
DOI: 10.1016/s2055-6640(20)30967-5